Tuning Depression Circuits Using Deep Brain Stimulation

Air date: Wednesday, February 17, 2010, 3:00:00 PM Timedisplayed is Eastern Time, Washington DC Local Category: Wednesday Afternoon Lectures Description: Critical to development of deep brain stimulation (DBS) as a novel therapy for treatment resistant depression has been the evolving characterization of brain systems mediating normal and abnormal mood states as well as those mediating successful and unsuccessful response to various antidepressant interventions. Building on converging functional neuroimaging evidence implicating the subcallosal cingulate as a critical node within this depression network, we targeted this region adapting neuromodulation techniques routinely used to treat Parkinson's disease and other movement disorders. The theoretical and data-driven foundation for piloting this new procedure as well as long-term clinical and imaging findings from ongoing experimental studies will be presented. The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. Author: Dr. Helen Mayberg Runtime: 01:08:15 Permanent link: videocast.nih.gov



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